Here's how I do it:
Default Spell Layout in my first 8 - whatever I want to mem immediately.
Buffs that need regular casting on my next 8: Charisma Buff, Shielding Spell, Clarity, Augment, Haste, Invis
Buffs/Stuff that need occasional casting on my next 16: AC Buff, Strengthen, Rune, Bedlam-line, See Invis, Invis Vs. Undead, Soothe, Pacify
Random useful utility stuff on page 3: Enduring breath, Levitate, etc.
8 most useful illusions to start page 4: (Human, Troll, Air Elemental, Water Elemental, Tree, 3 of your choice)
8 most useful crafting spells to end page 4.
Everything else is shifted to the back in roughly the order it's acquired, never to be looked at again.
Basically, I never have to use anything except Page 1 and 2 in-combat, and I almost never need to use page 2.
-Cross
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