What error do you get? Did you remember to start the game with the "no patch" flag? I also force it to run on one core only, otherwise animations are glitchy even though the game is playable.
My everquest.sh launcher has these two lines inside:
Code:
cd ~/.wine/drive_c/Program\ Files/Sony/EverQuest
taskset -c 0 padsp wine eqgame.exe patchme