Weaken is overwritten by Enfeeblement (just tested to make sure). They're in the same line, so the higher spell replaces the lower. Going forward, enchanters expand to two lines of physical debuffs and those do stack. Listless Power and Insipid Weakness stack, for instance. The unfortunate thing is that outside of dueling, these debuffs are fairly innefective and you're much better off with the tash line and slows if you want a debuff that really does something.
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