You will always have fizzles.
I would never consider dropping the macro.
If you fizzle (far less common than not fizzling), you still get back to back mana ticks for 1 click.
If you manually click, you will still get fizzles at the same rate, but 95% of the time that you don't fizzle you'll be clicking 3 buttons vs 1. When you DO fizzle ... you'll get that extra cast at the cost of 4 clicks vs the 1 click that failed. Even with the fail ... you ... still ... got ... 2 med ticks ... and ... didn't ... lose ... hitpoints.
Feel free to make it more labor intensive if you want.
I wouldn't.
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