For plate type melee, if you're going to get plate / banded / bronze armor early on, then the initial weight of that plus bags ( 3.0 wt for each basic backpack), multiple weapons to keep your skills near your level cap, in addition to loot / coin ( don't forget to bank excess and convert coin up to plat at the banker to reduce weight); It will all add up faster than you think.
It really depends if you want to try Min/Max ing, or being more comfortable running around and picking up loot to sell, depending on the starting strength of your race.
As far as casters go, you still get mana per Int past the soft cap of 200, it just is less per pt and you look for items with more +mana and less +int for overall max mana gain.
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