Depends what you're after. My take from EQ of this era on live (likely differs from TLP).
Exp wise. graveyards removed most of the risk of AE kiting and charm killing:
Bards AE kiting PoValor is King.
Necros did well in CoD.
Enchanters could do well in most zones.
Druids did well in PoTactics and HoH.
Money wise, it really depends on the economy and how top-heavy the server is. I can't imagine most items fetching a decent buck if you can run multiple instances for every different character ala TLP.
Most of the stuff that I remember being worth good money in PoP was way the fuck out of the way from anywhere 65s wanted to exp. The exception was E-Plane Bows and crafted E-plane armor. I'd be very surprised if these retained value on a top heavy server. There's a ton of good items from PoP that don't end up being worth dick because of supply. BoT minis, Piglet/Overseer, random zone drops like Wingblade, etc.
Necros could make a killing farming the mouth in Torment for Putrescent Blood for Ceramic Shackles.
If geared enough, an SK (and for most of this stuff, a paladin) can solo old raid mobs fairly easily. Trakanon has some useful BP clicks, some Dragon Haste/Scales still fetch a decent buck from twinks and bards. Tribute in GoD helps this. But most importantly, Divine Intervention was the most expensive spell in PoP. It's a required spell where there aren't many copies entering the market and 15% of the population are clerics. Compare DI to Torpor here and then realize people are actively killing Torpor-dropping mobs here. You won't be able to solo VP (NPC regen > your shitty dps), but you can trio it with a cleric and a DPS.
With CoS + FD, 65 necro or SK is going to be mobile enough and strong enough to farm a variety of CT nameds at once. FT3 Boots, Mosquito Leg Earring, Shield of Striding, etc. were all worth a lot of dough.
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