It will work with maestro hand, I had a rogue MQ for mine. I can't tell you on the rest. A lot of the epic is doing combines which can't be MQ'd.
As long as the NPC cons the same to you both (amiable, indifferent, etc) there shouldn't be a problem.
__________________
Butchh | Facetious | Knockers
Jayce | Briefs | Squash |