19 malaise seems like a good spell to throw around at higher levels imo. I feel like it makes a noticable difference but that the mana cost is too high to be worthwhile when your damage spells, slows, and roots are the same cost as malaise itself. When you're casting expensive dots and nukes and slows where a single resist is more expensive than several malaise casts, it seems nice to quickly throw out.
The bigger debuffs seem like they'll only be useful for stuff like a long fight with an ice giant or alizewsaur, putting on a chanter pet, etc., when you finally have enough Mana and Mana/hp regen that you can afford to spend hundreds of Mana on a cast or two in hopes of resists evening out for the rest of a long fight.
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