I make use of my numpad a lot; I find it extremely useful.
0: /stopsong
1-8: /stopsong /cast #
9: inventory clicky item (or some other useful macro)
+: First person camera
-: User defined camera
.: Toggle between last two targets
/ and *: Other macros of choice, I typically put /pet commands here
With my right hand on the numpad, it's only a short movement to grab the mouse for an instrument switch and it leaves my left hand free for WASD, assist hotkeys, etc... sometimes even *gasp* typing while twisting.
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