She is very doable at 12, no matter her con (she'll be yellow or red, and the only difference is a few more resists when red). I even took her at 11, but died quite a few times trying.
Summon a strong pet (you should be able to get a white-con pet at 12), and send him in first. Cast heat blood after he has aggro, then chain-cast darkness till it sticks. Run far enough away to get enough distance that you can cast fear before she hits you. If she resists, run again. It'll take some time before it gets "easy", and you might die a few times until you get the hang of it, but once you do it's a nice camp.
For extra credit, kill Brother Estle and the guard in the next house. They're easy to take one at a time, and they're lower-level than Misty so you shouldn't have much trouble. You can kill the two NPCs in the trees to the east as well, but they'll be tough to split at your level, especially if you're trying to kill Misty every 6 minutes too.
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