You use your nukes, but because you can cannibalize/chloro for mana regen it's not needed to sit and med the entire time. In groups where there's a cleric healing i always have more than enough mana to keep the entire group buffed/hasted and melee/nuke and still plenty for off-heals. In classic mobs generally don't hit hard/have enough HP to warrant a slow in a group scenario, so it frees up quite a bit of mana to nuke.
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