Sometimes that little bit of extra mana can save you just like that little bit of hp could save you. With so many ways to convert hp to mana and vice versa, I think the main considerations are returns from+stats and which is harder to max. You get way more mana per wis than you get hp per sta and get sta buffs like others have said.
Also the cazic clickie neck gets seriously overlooked. Lots of fun to have leveling up, and with the Warrens out its a relatively easy faction grind and easy quest to boot.
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