When to slow/malise/other debuffs?

[Bantam 1]

Alright I never played a shaman on live; even a low level one. I've watched them a lot and played an enchanter at a raid level, but not low level.

My slow, malise (sp?), melee stat decrease etc all have a massive amount of hate associated with them. I'm not too squishy so its not the worse thing that could happen.
However, I'm looking ahead to Sebillis, CoM, raiding and thinking - this could be lethal. I've waited to 75-65% to slow and I still pull aggro...

So how is this handled? I don't remember shaman getting insta gibbed back on EQlive during classic.

Edit - anyone able to help me with the bear for the totemic helm? or the kedge keep part? Both seem oddly "Whoa damn" in terms of mid level armor quests. Personally - was a little surprised that the bear is around 2 (apparently roaming...) shaman blenders.