End Times

[Jobaber]

Back to revelations!

Seal 1 - White horse: A lamb wearing a white robe, a crown was given unto him: and he went forth conquering.
Seal 2 - Red horse: Peace will be taken from the earth and man should kill one another: and there was given unto him a great sword.
seal 3 - Black horse - A measure of wheat for a denarius, and three measures of barley for a denarius; but do not hurt the oil and the wine.

Im stopping there, because I think we're right on track and in the middle of 2.

Seal 1 - The white robe, and crown and the lamb represent our freedom, the covid protocols, and the conditioning to make us willing to give them up for the greater good.

Seal 2 - Wars, and World war III will be declared, the great sword likely means the nuke that will soon be going off.

Seal 3 - Represents the inflation and famine that will plague the earth as a result of ww3. Though many will starve, the wealthy will enjoy the luxuries of oil and wine.

Hey, I could be wrong, but Im just waiting for the steps to take one off the road mapped out in the bible.

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[magnetaress]

sounds 100% accurate to me

the only way to stop suffering is to understand that this isn't personal

it's not about you personally

and through G-d's will a new and beautiful earth will be reborn from the ashes of our folly

[aussenseiter]

Originally Posted by Jobaber [You must be logged in to view images. Log in or Register.]

Seal 1 - White horse: A lamb wearing a white robe, a crown was given unto him: and he went forth conquering.


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[Jobaber]

Originally Posted by magnetaress [You must be logged in to view images. Log in or Register.]

the only way to stop suffering is to understand that this isn't personal

wise words!

[Jobaber]

Originally Posted by aussenseiter [You must be logged in to view images. Log in or Register.]

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What is that belanciaga the game? [You must be logged in to view images. Log in or Register.]

[Jobaber]

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Scientists Have Reached a Key Milestone in Learning How to Reverse Aging

In the Cell paper, Sinclair and his team report that not only can they age mice on an accelerated timeline, but they can also reverse the effects of that aging and restore some of the biological signs of youthfulness to the animals. That reversibility makes a strong case for the fact that the main drivers of aging aren’t mutations to the DNA, but miscues in the epigenetic instructions that somehow go awry. Sinclair has long proposed that aging is the result of losing critical instructions that cells need to continue functioning, in what he calls the Information Theory of Aging. “Underlying aging is information that is lost in cells, not just the accumulation of damage,” he says. “That’s a paradigm shift in how to think about aging. “

His latest results seem to support that theory. It’s similar to the way software programs operate off hardware, but sometimes become corrupt and need a reboot, says Sinclair. “If the cause of aging was because a cell became full of mutations, then age reversal would not be possible,” he says. “But by showing that we can reverse the aging process, that shows that the system is intact, that there is a backup copy and the software needs to be rebooted.”

In the mice, he and his team developed a way to reboot cells to restart the backup copy of epigenetic instructions, essentially erasing the corrupted signals that put the cells on the path toward aging. They mimicked the effects of aging on the epigenome by introducing breaks in the DNA of young mice. (Outside of the lab, epigenetic changes can be driven by a number of things, including smoking, exposure to pollution and chemicals.) Once “aged” in this way, within a matter of weeks Sinclair saw that the mice began to show signs of older age—including grey fur, lower body weight despite unaltered diet, reduced activity, and increased frailty.

The rebooting came in the form of a gene therapy involving three genes that instruct cells to reprogram themselves—in the case of the mice, the instructions guided the cells to restart the epigenetic changes that defined their identity as, for example, kidney and skin cells, two cell types that are prone to the effects of aging. These genes came from the suite of so-called Yamanaka stem cells factors—a set of four genes that Nobel scientist Shinya Yamanaka in 2006 discovered can turn back the clock on adult cells to their embryonic, stem cell state so they can start their development, or differentiation process, all over again. Sinclair didn’t want to completely erase the cells’ epigenetic history, just reboot it enough to reset the epigenetic instructions. Using three of the four factors turned back the clock about 57%, enough to make the mice youthful again.

“We’re not making stem cells, but turning back the clock so they can regain their identity,” says Sinclair. “I’ve been really surprised by how universally it works. We haven’t found a cell type yet that we can’t age forward and backward.”

Rejuvenating cells in mice is one thing, but will the process work in humans? That’s Sinclair’s next step, and his team is already testing the system in non-human primates. The researchers are attaching a biological switch that would allow them to turn the clock on and off by tying the activation of the reprogramming genes to an antibiotic, doxycycline. Giving the animals doxycycline would start reversing the clock, and stopping the drug would halt the process. Sinclair is currently lab-testing the system with human neurons, skin, and fibroblast cells, which contribute to connective tissue.

In 2020, Sinclair reported that in mice, the process restored vision in older animals; the current results show that the system can apply to not just one tissue or organ, but the entire animal. He anticipates eye diseases will be the first condition used to test this aging reversal in people, since the gene therapy can be injected directly into the eye area.

“We think of the processes behind aging, and diseases related to aging, as irreversible,” says Sinclair. “In the case of the eye, there is the misconception that you need to regrow new nerves. But in some cases the existing cells are just not functioning, so if you reboot them, they are fine. It’s a new way to think about medicine.”

That could mean that a host of diseases—including chronic conditions such as heart disease and even neurodegenerative disorders like Alzheimer’s—could be treated in large part by reversing the aging process that leads to them. Even before that happens, the process could be an important new tool for researchers studying these diseases. In most cases, scientists rely on young animals or tissues to model diseases of aging, which doesn’t always faithfully reproduce the condition of aging. The new system “makes the mice very old rapidly, so we can, for example, make human brain tissue the equivalent off what you would find in a 70 year old and use those in the mouse model to study Alzheimer’s disease that way,” Sinclair says.

Beyond that, the implications of being able to age and rejuvenate tissues, organs, or even entire animals or people are mind-bending. Sinclair has rejuvenated the eye nerves multiple times, which raises the more existential question for bioethicists and society of considering what it would mean to continually rewind the clock on aging.”

[aussenseiter]

Originally Posted by Jobaber [You must be logged in to view images. Log in or Register.]

What is that belanciaga the game? [You must be logged in to view images. Log in or Register.]

They were playing it on the GDQ yesterday (Friday the 13th) [You must be logged in to view images. Log in or Register.]

[magnetaress]

Originally Posted by Jobaber [You must be logged in to view images. Log in or Register.]

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Scientists Have Reached a Key Milestone in Learning How to Reverse Aging

I was going to write about this today.

Glad you shared.

[aussenseiter]

Originally Posted by magnetaress [You must be logged in to view images. Log in or Register.]

I was going to write about this today.

Glad you shared.

[magnetaress]

Not planning on getting the de aging shots.