When to put down Luminescent Staff

[Lukile]

If you're planning on mostly charming, I would sell it.

If you're planning on mostly quadding, I would keep it until you no longer need it to finish the kills.

I used lumi staff for spirocs from 46-52, and then sold it. It was great for those levels, but I was more interested in kedge/bear pits for leveling than quadding.

The pp was more value for me in getting 50s spells, velious armor gems, etc. than mostly sitting in my inventory doing nothing. YMMV.